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Originally developed as a medication for managing Type 2 diabetes, semaglutide has a unique ability to mimic a hormone called GLP-1 (glucagon-like peptide-1), which regulates appetite and blood sugar levels

It works by targeting the receptors of glucagon-like peptide-1 (GLP-1), a gut hormone involved in regulating your digestion, appetite, and blood sugar levels

Reduced appetite and food intake over months to years can lead to deficiencies in protein, iron, calcium, vitamin D, and B vitamins

4.3% of adults taking semaglutide vs 0.7% on placebo quit the trial because of gastrointestinal issues

If heartburn or acid reflux symptoms persist beyond 24 weeks despite making dietary changes, adequate hydration, and conservative care, discuss with your doctor to change the dosage or switch medication to another GLP-1 agonist

Doctors say its essential for patients to understand they could fall into either camp responder or non-responder even though the data suggests its more likely a person will respond