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If needed, we can advise whether further medical review is appropriate

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In agreement with results in iWAT from mice under cold-exposure 24 or caloric restriction 50 , enrichment in eosinophils and, importantly, a rise of the IL4 + subpopulation, was found in both SVF and eWAT from G49-treated DIO mice together with elevated Il4 and Il13 gene expression, a M2 immune signature related to beiging 50

Patients were mainly screened at two primary care settings although advertisement was also used for dissemination of the study

Bras Dermatol (2016) 91:5803