These results are significant when compared to other treatments
doi: 10.1007/s11064-014-1481-1
10.1152/ajpendo.00569.2010 16 ErionD
Like, if somebody has cardiovascular disease and has a narrowed coronary artery, you can put a stent in to open that artery and restore circulation, but you also have to treat the underlying disease that's marching in the background, the high cholesterol, the inflammation, with the drug, and you also need cardiovascular therapy
Effects on weight were seen primarily in people who took berberine in doses of more than 1 gram per day and for more than eight weeks
It has not progressed through regulatory channels, there are no approved human uses, and no registered clinical trials exist for it