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Biomarkers can be used to comprehensively monitor the physiological status of ASD patients during diagnosis, intervention, and treatment, which can aid in understanding the condition, judging the treatment strategy, and monitoring efficacy and prognosis ( Currently, mass spectrometry-based targeted proteomic or metabolomic approaches can effectively monitor multiple disease markers simultaneously (274) and utilized (275)

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And Novo Nordisk plans to initiate a global 68-week phase 3 trial in the second half of 2021 on the efficacy and safety of oral semaglutide 50 mg compared with placebo in 1000 people with obesity or overweight and comorbidities