PE934030: Galβ(1-3)GalNAc-α-PEG3-Azide label-new Antiproliferative factor (APF) is a

Antiproliferative factor (APF) is a sialoglycopeptide that contains the transmembrane segment of Frizzled 8

93 / An Fmoc-protected L-threonine building block carrying a GlcNAcβ1-3GalNAcα disaccharide

This probe can be used as a soluble inhibitor or immobilized on plates or sensors to investigate binding

Tri-GalNAc-β-Ala-PEG3-Biotin

65 / An Fmoc-protected L-threonine building block carrying an α-D-glucose residue

PE934030: Galβ(1-3)GalNAc-α-PEG3-Azide label-new Antiproliferative factor (APF) is aC20H36N4O13 540. 52 A core 1 T antigen (Gal1 3GalNAc) ligand equipped with an azide handle through a hydrophilic PEG3 spacer. The terminal azide couples to alkynes via copper catalyzed azide alkyne cycloaddition (CuAAC) or to DBCO and related strained alkynes via copper free click chemistry, forming stable 1,2,3 triazole linkages. This compound presents the core 1 T antigen (Gal1 3GalNAc), a tumor associated carbohydrate antigen and ligand for