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In a smaller cohort of patients with more severe CD phenotypes, including 17% with perianal involvement and 24% with penetrating or fistulizing disease, numerical reductions across outcomes were observed in the GLP-1RA group, but these differences did not reach statistical significance (104)
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individual results vary significantly
Berberine's effects are gentler and work through metabolic optimization rather than appetite regulation
Additionally, its important to discuss any concerns you have about potential side effects with your doctor or other healthcare professional to make sure the medication is right for you