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This can increase the likelihood of gastrointestinal effects like nausea and diarrhea

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Protocols must strictly specify the discontinuation-to-conception timeline (washout duration) to minimize time-related heterogeneity and ensure comparable exposure windows across study arms

MC1R and Melanocortin 1 Receptor Documentation Context MC1R is a melanocortin receptor that binds melanocyte-stimulating hormones and ACTH-related ligands in receptor biology records [6]

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