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Many studies have pointed out a role for oxidative stress in ARDS and shown a protective effect of GSH precursors

Thacher T, Gambillara V, da Silva RF, Silacci P, Stergiopulos N (2010) Reduced cyclic stretch, endothelial dysfunction, and oxidative stress: an ex vivo model

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Additionally, melanocortins such as -melanocyte-stimulating hormone (-MSH), produced by both keratinocytes and melanocytes, activate the melanocortin-1 receptor (MC1R) on melanocytes, further enhancing their antioxidant capacity

Ethics declarations Competing interests J.M.R has been a paid consultant to Aquestive Pharmaceuticals, Danone Nutricia, Mallinckrodt, Eisai Pharma and Zogenix, and has served on the Scientific Advisory Board of The Charlie Foundation for Ketogenic Therapies (Santa Monica, CA, USA)

Respiratory protease/antiprotease balance determines susceptibility to viral infection and can be modified by nutritional antioxidants