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The last comparison was of the concentrations of different metabolites between arginine and proline media for gdh3 / gdh3 mutant compared to those in the wild-type strain under the same conditions (comparison between gdh3 -R/ gdh3 -P and WT-R/WT-P)

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401 In addition, MDD is associated with significant decreases in astrocytic glutamate transporters and glutamine synthetase, impairing neurotransmission

doi: 10.1210/jc.2008-2808 57 NyuntOCotterillAMArchboldSMWuJYLeongGMVergeCFet al