Smits, University of Copenhagen, Denmark Reviewed by Rafael Rivas-Santisteban, University of Barcelona, Spain Ulrik Becker, University of Southern Denmark, Denmark Updates Copyright 2023 Jerlhag
Servings Per Container: About 30
Your Action Plan (The Short Version): 2-3 Months Before Conception: This is when you stop your GLP-1 medication (coordinate with your prescribing doctor), switch to reliable contraception if youre using oral contraceptives, begin prenatal vitamins with 400-800mcg folate, and schedule a preconception appointment with your OB/GYN
A long-standing hypothesis for why GLP-1 (and other gut peptides for that matter) are increased after RYGB is that the shorter length of small bowel leads to more rapid nutrient delivery further down into the GI tract where the majority of L-cells are located (62)
In contrast, peptides whose human effects remain weak or inconsistent despite adequate exposure may warrant lower priority absent new mechanistic insights
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