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This review firstly illustrated the detailed drug resistance cellular and molecular mechanisms underlying HGSOC chemotherapy, which can pave the way for future studies in HGSOC drug resistance practices

UA Degradation Activity of PDA@Pt Pt NPs serve as efficient mimics of uricase in the oxidation process of UA, catalyzing its degradation into more soluble substances without generating H 2 O 2 [18]

Much of the safety data comes from animal studies, where researchers report on tolerance and effects in those models