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Eli Lilly is betting big on retatrutide as the next pillar of its obesity portfolio after its weight loss injection Zepbound and its upcoming pill

For example, if youre on the second-highest available dose of an injectable GLP-1, then it may be reasonable to start with the comparable dose of the pill, says Dhvani Doshi, MD, MPH, medical director and obesity medicine physician at University Hospital in Newark, New Jersey

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Subjects experiencing significant GI intolerance may remain at a lower dose or reduce by one titration step