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This creates procurement volatility, pricing pressure, and longer production lead times

doi:10.1152/ajpendo.00030.2002

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After 46 weeks of treatment: 0.6 mg dose: 6.2% mean body weight reduction 2.4 mg dose: 12.5% mean body weight reduction 3.6 mg dose: 13.2% mean body weight reduction 4.8 mg dose: 14.9% mean body weight reduction (all randomized) 4.8 mg dose: 18.7% mean body weight reduction (completers only) Placebo: 2.8% mean body weight reduction Among completers at the 4.8 mg dose, 68.8% achieved at least 10% weight loss, 67% achieved at least 15%, and 40% achieved at least 20% weight loss

Overnight carrier

Injecting air creates positive pressure inside the vial that forces liquid back through the needle tract on subsequent draws, introducing contaminants that compromise sterility over the 28-day use window