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P = 0.2823)

Chapter 120

D-Nle-X-Ile-NH-(CH 2 )5-CONH 2 derivatives were found to compete with Hinge for HGF binding and exhibited a range of affinities for HGF, with s ranging from 1.37xl0 ~7 - 1.33xl O " 'M (Figure 23)

For activation by sodium dithionite, a 50 mM Na 2 S 2 O 4 stock solution in PBS was added to the mixture containing compound 6c to a final concentration of 5 mM, followed by incubation at 37 C

Erhola M, Kellokumpu-Lehtinen P, Mets-Ketel T, Alanko K, Nieminen MM