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In people without pernicious anemia, about 0.5 g/day of B12 is reabsorbed by enterohepatic circulation in which B12-containing bile is secreted by the liver into the digestive tract where the B12 is then reabsorbed via intrinsic factor

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After careful consideration of the comments, for CY 2026 we are finalizing rates consistent with the groupings illustrated in the proposed rule in the interest of transparency and consistency