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Depletion of USP11 inhibits cell proliferation and induces ROS-mediated stress-induced ferroptosis, an effect that can be mitigated by overexpression of NRF2

Arreola, R., Quintero-Fabin, S., Lpez-Roa, R

Hoggard N, Cruickshank M, Moar KM, Bestwick C, Holst JJ, Russell W, Horgan G

L-NAME induces high blood pressure by acting as nitric oxide synthase (NOS) inhibitor ( 2 production and malondialdehyde (MDA) level in plasma and thoracic aorta and increased the level of SOD and CAT antioxidant enzymes, suggesting the potency of MO against oxidative stress-related hypertension in L-NAME rats ( via NOS-sGC dependent signaling