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Evidence that tight junctions are disrupted due to intimate bacterial contact and not inflammation during attaching and effacing pathogen infection in vivo

Oxidative stress is an imbalance between free radicals (unstable molecules that can damage cells) and antioxidants (molecules that neutralize them)

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10.1016/j.cbi.2014.10.016 165 LynchM

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Potential side effects include: Water retention (especially early in the protocol) Mild joint discomfort or stiffness Temporary fatigue or lethargy Flushing or warmth at the injection site Headaches (typically mild and transient) Most side effects are dose-dependent and resolve with dosage adjustment