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1,5 A randomized clinical trial using exenatide demonstrated a reduction in the alcohol cue reactivity in these notable neural reward zones on functional magnetic resonance images and a decrease in dopamine transporter availability

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doi: 10.1080/01616412.2016.1145914 198 PanagakiTMichaelMHolscherC

Efficacy many companies, such as Eli Lilly or Zealand Pharma, are working on improving efficacy in terms of percentage weight loss or focussing on specific sub-niches, like liver diseases

Another study suggests that increasing basal insulin above 0.5 Units/kg BW/day may not improve glycemic control and may also result in weight gain and increased risk of hypoglycemia [12]