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While GLP-1R expression has been demonstrated in rodent thyroid C cells, the receptor has generally not been detected in healthy human or primate thyroid C cells, or has been detected only in small subsets

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A longer study (mean follow-up of 3 years), found a lower risk for a composite outcome of kidney replacement therapy, or kidney failure-related hospitalization or death in initiators of GLP-1 RAs compared with DPP4i [29]

This article systematically summarizes the extra-pancreatic effects of GLP-1RAs, and discusses the therapeutic effects and possible mechanisms of GLP-1RAs on various diseases