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In RCTs, there are tightly regulated cohorts based on stringent in- and exclusion criteria, thereby reducing generalizability

however, it is not currently approved by the TGA for this indication

Night sweats, in particular, can be associated with anxiety or sleep disturbances

Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces Alzheimer disease-associated tau hyperphosphorylation in the hippocampus of rats with type 2 diabetes

The injection is available in higher doses compared to the tablets for weight loss

This is a known phenomenon where neurons that had adapted to chronic hyperglycemia react adversely to rapid glycemic normalization