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Reduced Caloric Intake GLP-1 medications work primarily by reducing appetite and food intake

Reusing a needle introduces contamination from the previous injection site and increases coring risk from a blunted needle tip

While it has also proven to be effective for weight loss, its weight-reducing effects may not be as pronounced as those seen with tirzepatide

Chistiakova et al., 2014, 2015

The researchers also noted that 23.5% (95% CI, 22.3-24.8) of people meeting FDA indications for tirzepatide reported using medications that may slow gastrointestinal motility, which could increase gastrointestinal adverse effects when combined with any GLP-1 receptor agonist

Wang GL, et al