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In contrast, the 2,3-diamino substitution in the 1MQ scaffold (2,3-diamino-1MQ) displayed high passive permeability (Table 1), but moderate bi-directional active transport with moderate efflux ratio (Table 2)

doi: 10.1152/jappl.1984.57.5.1577 297 GravettMGHittiJHessDLEschenbachDA