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In addition, exendin-4 protects against cardiac ischemia/reperfusion injury in rats by enhancing antioxidant levels and inhibiting c-Jun NH2-terminal kinase (JNK)/p 66 Shc/NADPH oxidase axis [13]
Cysteine residues in Keap1 act as sensors for electrophiles and oxidants, and their oxidation leads to the release and subsequent translocation of Nrf2 into the nucleus where it can bind to the ARE4 sequence in the promoter region of genes involved in antioxidant defense (Moinova and Mulcahy 1999)
For plots c, d, and e, point estimates are represented as circles, and horizontal bars indicate 95% confidence intervals
It can be used during or after an advanced supplementation cycle, or as a standalone recovery product
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