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Symptoms following acute NSAID overdose are usually limited to lethargy, drowsiness, nausea, vomiting and epigastric pain, gastrointestinal bleeding can occur but very rarely, hypertension, acute renal failure, respiratory depression and coma

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When I met with the editor of the BNF a year or two again she told me that any change in the treatment would have been based on evidence based research

For 5mg vials, use 1-2 mL

Toxicity appears low, but long-term human safety is unknown