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A prospective, randomized pilot trial of model-based warfarin dose initiation using CYP2C9 genotype and clinical data

Neutrophil proteinase 3 and dipeptidyl peptidase I (cathepsin C) as pharmacological targets in granulomatosis with polyangiitis (Wegener granulomatosis)

10.3389/fmolb.2022.925700 58 ZhaoY.LuanH.JiangH.XuY.WuX.ZhangY.et al (2021)

Due to the exhaustion of cellular and extracellular GSH caused by numerous GSH-consuming pathways the severe inflammation and oxidative stress triggered by the viral infection steals GSH from crucial functions like NO-dependent vasodilatation, disallowing the patient of being protected from an inflammation that can become fatal

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The latter is effective in avoiding repeated thawing