Inflammations of the genitourinary tract are common clinical manifestations of Candida infections, which include vulvovaginal candidiasis (VVC) in women, balanitis and balanoposthitis in men, and candiduria in both sexes [119]
Meanwhile, mitochondrial damage mediated by PCD protein 2 can increase the generation of mitochondrial reactive oxygen species, synergistically inducing autophagy and ferroptosis [113]
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It has been extensively used as an inducer of oxidative stress in vitro models