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Am J Phys Heart Circ Phys 298:H2174H2191 Wieczor R, Gadomska G, Ruszkowska-Ciastek B, Stankowska K, Budzynski J, Fabisiak J, Suppan K, Pulkowski G, Rosc D (2015) Impact of type 2 diabetes on the plasma levels of vascular endothelial growth factor and its soluble receptors type 1 and type 2 in patients with peripheral arterial disease

J Biotechnol Biomater

In user feedback, 92% reported visible glow, and 88% noticed improved skin tone and texture within 6 weeks of daily use

In the After picture you'll see that it's gone & it didn't really leave a bad pigmentation/dark spot compare if i'm just going to use an ordinary soap

Preclinical studies document significant brain concentrations after systemic (including oral) administration, with behavioral improvements in hippocampal-dependent tasks confirming functionally relevant CNS penetration (PMID: 23055539)

However, many sheep farmers use a dose rate of between 0.5-1ml, giving variable lengths of cover