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While our findings indicate that NF-B can specifically bind to EAAT3 promoter regions in certain cell types, multiple pathways and factors are known to regulate EAAT3, including the NRF2-ARE pathway [51], the RFX1 transcription factor [52], NFAT5/TonEBP [53], and ATRA [54]

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The sponsor was involved in the original conception of the study