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I believe these medications have such broad effects because a lot of health problems begin with disruptions in insulin resistance [abnormalities in how the body handles glucose] and inflammation, says Jamy Ard, MD, a professor of epidemiology and prevention at Wake Forest University School of Medicine in Winston-Salem, North Carolina

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Ageing and inherited genetic variants affecting enzymes involved in one carbon metabolism, including MTHFR , may further reduce the efficiency of methylation

For an approved GLP-1 medication context, see Semaglutide Weight Loss Medication

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