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Discuss eligibility and medication choice with your clinician

However, if this severe elevation is accompanied by symptoms such as chest pain, severe headache, shortness of breath, neurological symptoms, or confusion, patients should call 911 immediately as this represents a hypertensive emergency requiring urgent treatment

So what is the evidence around safety then

Endocrinology (2012) 153(3):153847

GLP-1 medications are prescription drugs containing synthetic peptides that directly activate GLP-1 receptors, producing significant weight loss of 15-21% over 72 weeks

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