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Metformin improves ovarian follicle dynamics by reducing theca cell proliferation and cyp-17 expression in an androgenized rat model

This epithelial disruption was linked to elevated serum LPS, confirming increased intestinal permeability and microbial translocation

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Furthermore, R-ketamine has also been shown to attenuate delirium and cognitive impairment induced by high doses of LPS, reducing the release of inflammatory cytokines both systemically and centrally [80]

In the high-dose group, intracellular glutathione levels increased by 3035% in red blood cells, plasma, and lymphocytes, and by an astonishing 260% in buccal (inner cheek) cells