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doi: 10.4049/jimmunol.1601346 81 GanesanRRasoolM
10.3390/molecules191119066 11 ChangC
The Wolverine Stack Composition & Key Research Facts Components: BPC-157 (pentadecapeptide, 15 amino acids) and TB-500 (Thymosin Beta-4 fragment) Research designation: Widely referred to as the Wolverine Stack in the pre-clinical peptide research community BPC-157 primary mechanism: VEGFR2/ERK1/2 activation, nitric oxide signalling, fibroblast migration, angiogenesis, ECM stabilisation TB-500 primary mechanism: G-actin sequestration, cytoskeletal reorganisation, keratinocyte and endothelial cell migration, stem/progenitor cell mobilisation Synergy mechanism: BPC-157 organises and vascularises tissue
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