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Sulfotransferase is available mainly in liver, but can be found in kidney, intestine and other tissues Sulfation Also occur for endogenous compounds, such as steroids, thyroxin, catecholamine and heparin

It is the selenoenzymes that play a vital role in antioxidant defense, regulation of the thyroid function, and immune system support

10.1016/j.redox.2020.101426 79 LeeH

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There is also some evidence that the medication may contribute to worsening retinopathy, a disease affecting the retina