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Doxorubicin has been reported to induce significant senescence in breast cancer cell lines, particularly promoting SA--gal expression in MCF7 cells line indicating a substantial impact of p53 on senescence induction [58]

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and J.M.D.), by a grant from the Alzheimers Association (23AARG-1029665 to D.W.L.), and by startup funds from UW-Madison