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Diabetol Int 16 , 448456 (2025)

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In another trial, semaglutide demonstrated a 26 percent reduction in major adverse cardiovascular events in patients with type 2 diabetes at high cardiovascular risk

Our findings suggest that semaglutide combined with metformin results in more substantial reductions in glycated hemoglobin, fasting blood glucose, HOMA IR, BMI, and lipid levels compared to metformin alone