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This upregulation leads to an increased expression of lipogenic genes, including sterol regulatory element-binding proteins (SREBP1c) and diacylglycerol acyltransferase-2 (DGAT2), which suggests that miR-370 provides a further point of regulation of this pathway 86

5-amino-1-methylquinolinium is appropriate for metabolic syndrome applications where pathogenic enzyme overexpression produces dysfunction due to its targeted effects on disease-relevant tissues

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