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demonstrated that long-term GHRH analog administration in aging adults produced sustained increases in GH secretion and IGF-1 levels along with improvements in body composition (3)

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Exposure to ionizing radiation is well known to promote oxygen radical formation within biological systems through radiolysis (interaction of radiation and water).12 Hypoxia or/and hyperoxia condition in cells has been noted to generate numerous oxygen-derived radicals.13 Besides, a couple of therapeutic drugs such as acetaminophen have been reported to cause oxidizing effects on cells, consequently leading to formation of oxygen radicals through the activity of drug metabolizing enzymes known as cytochrome P -450 system.14 5

However, there are instances where discontinuing the medication leads to weight regain

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There were 81 participants that began the study, but 6 withdrew prior to completion