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As we age: Telomeres gradually shorten Cellular repair declines Cellular senescence increases Biological aging accelerates Research suggests Epitalon may stimulate telomerase activity, potentially helping maintain telomere length and supporting cellular longevity

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o Dapagliflozin is likely to be ineffective to improve glycemic control in patients with eGFR less than 45 mL/min/1.73 m2

Lancet 402 , 670671 (2023)

[4] The most frequently reported adverse effects include transient gastrointestinal discomfort-nausea, vomiting, abdominal cramps, or diarrhea-particularly when large doses are delivered rapidly