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At present, American company Altimmunes GLP1/glucagon dual receptor pemvidutide is being evaluated in the clinic to treat obesity and non-alcoholic steatohepatitis (NASH)

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doi:10.1016/j.freeradbiomed.2006.06.010 Lieber CS (2004) CYP2E1: from ASH to NASH

In the pivotal MAESTRO-NASH of THR agonist Rezdiffra, steatohepatitis resolution was seen in 30% of patients on a 100mg dose, compared to 10% with placebo, after 52 weeks

For additional details on the OPPS proposal for skin substitutes, please see the CY 2026 OPPS/ASC proposed rule with comment period