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Glutamatergic neurotransmission is responsible for many cognitive, motor, sensory, and autonomic nervous activities [220,221,222]

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These analyses are then presented to the Ontario Health Technology Advisory Committee, whose mandate is to examine proposed health technologies in the context of available evidence and existing clinical practice, and to provide advice and recommendations to Ontario health care practitioners, the broader health care system, and the Ontario Ministry of Health and Long-Term Care

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GLP-1 medications help regulate appetite by slowing gastric emptying and increasing feelings of fullness after meals