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ENaC is thought to be the main receptor for the detection of NaCl or the taste salty [46]

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Some research indicates that consuming allulose (typically 5-10g with meals) alongside carbohydrate-containing meals may modestly attenuate postprandial blood glucose excursions

thus, there is a smaller window for weight loss, as body weight defence mechanisms have a greater role in lean mice, potentially confounding the absence of treatment effects

Investigation into GLP-1-based diabetes therapies concluded

GLP-1RAs, as an important class of drugs for the treatment of T2DM, shows significant advantages in blood glucose control, weight loss, cardiovascular protection and kidney benefit (Ussher and Drucker, 2023