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Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape

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(2) normal temperature plus exogenous GSH treatment (NT+GSH): added 0.25 mM GSH in nutrient solution one day before the treatments and maintained at 0.25 mM GSH in the nutrient solution during the treatment period

Glu is converted to gamma-glutamylcysteine through gamma-glutamylcysteine synthetase

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It could come with nausea, dizziness, headaches, or other generalised symptoms