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Managing Drug Interactions and Combined Risks Dehydration is a significant concern for CKD patients on GLP-1 medications, especially when combined with drugs that affect fluid balance
For some, this means adding capsules to a morning routine
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Gradual taper of dose The Approach For patients who want to find the lowest effective dose or to discontinue completely, a gradual taper means stepping the GLP-1 dose down in small, planned increments (typically using the same titration steps as initiation, but in reverse) to test whether benefit can be maintained with less medication or none at all