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4.3 Modulation of chemokine dysregulation Chemokines are small, secreted proteins produced by both structural and immune cells that regulate immune responses at sites of inflammation by directing immune cell migration through interactions with G protein-coupled receptors, including CC chemokine receptors (CCR) and CXC chemokine receptors (CXCR) (Liu J

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Mol Med Rep (2018) 18(4):362530

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(PubMed) Constantinou C, Papas A, Constantinou AI