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Tirzepatide is a novel glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for the treatment of type 2 diabetes mellitus and chronic weight management

Perrone S, Longini M, Bellieni CV, Centini G, Kenanidis A, De Marco L, Petraglia F, Buonocore G (2007) Early Oxidative Stress in Amniotic Fluid of Pregnancies with Down Syndrome

Astrocytes, the major glial support cells in the CNS, are indispensable in the regulation of GSH homeostasis

Mentioned reactive aldehydes, as well as isoprostanes, particularly F2-isoprostanes, are bioactive compounds formed via nonenzymatic peroxidation of arachidonic acid (AA), serving as reliable biomarkers for assessing oxidative stress status in various clinical conditions 89

Chang KH, Muftuoglu M, Zhang W, Basyal M, Ostermann L, Fogler WE, Magnani JL, Andreeff M