Osmotic laxatives like polyethylene glycol are generally safe with GLP-1
The approval is supported by data from the Phase I/II TRIDENT-1 trial, where treatment with Augtyro resulted in a 58% confirmed objective response rate (cORR) in TKI-nave patients, of which 15% were complete responses
Both Wegovy and Rybelsus should be avoided in patients with a history of medullary thyroid cancer or a family history of multiple endocrine neoplasia cancer syndrome type 2 (MEN-2)
Key Takeaways Semaglutide, used in Wegovy and Ozempic, has been linked to an increased risk of NAION, which can cause sudden vision loss
These medications already affect how your body processes nutrients, so your food choices can help maximise benefits and minimise side effects
J Clin Invest (2014) 124(6):245663.10.1172/JCI72434 60 MirasADJacksonRNJacksonSNGoldstoneAPOlbersTHackenbergTet alGastric bypass surgery for obesity decreases the reward value of a sweet-fat stimulus as assessed in a progressive ratio task