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The pentose phosphate pathway generates NADPH from glucose, while mitochondrial enzymes produce NADPH to support glutathione recycling inside mitochondria [9]
In particular, overconsuming vitamins A, D, and E can be toxic, leading to side effects like irregular heartbeat, organ damage, hemorrhages, hemorrhagic stroke, and in extreme cases, even coma and death ( As water-soluble vitamins are not stored in your body, theyre less likely to cause toxicity from an overdose
Clinically and definitively, yes
Nat Rev Microbiol (2023) 21(1):5164
& Jankovic, J
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