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While EGFR family members can compensate IGF-IR inhibition and confer resistance to IGF-IR-targeted agents, IGF-IR can confer resistance to EGFR/ErbB2/ErbB3-targeted therapies as well

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The slow acetylator phenotype is caused by decreased or absent arylamine N-acetyltransferase in human liver.853(March 1990),968972,0021-9738 40

It is sometimes prescribed off-label to manage generalized anxiety, especially when traditional anxiolytics are not suitable

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