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While 20% reduction in muscle mass seems normal for someone losing weight, the problem is the length of time in which this muscle loss occurs, said Kumar

Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes across baseline HbA1c levels (STEP-HFpEF DM): a prespecified analysis of heart failure and metabolic outcomes from a randomised, placebo-controlled trial

Hypertension 60 , 833841 (2012)

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In vivo delivery of NanoLuc expressing plasmid DNA To evaluate DNA delivery efficiency, luciferase (Luc) activity was measured in major organs (liver, lung, spleen, kidney and heart) of 6-8 weeks-old female Balb/c mice