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A 2.5 mg dose of tirzepatide and a 0.25 mg dose of semaglutide are both "starting doses" that serve the same purpose, tolerance building, but the actual pharmacology behind each number is unique

Bernink FJ, Timmers L, Diamant M, et al

Immune-related adverse events and anti-tumor efficacy of immune checkpoint inhibitors

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GPx isoenzymes are all antioxidant enzymes that reduce potentially damaging reactive oxygen species (ROS), such as hydrogen peroxide and lipid hydroperoxides, to harmless products like water and alcohols by coupling their reduction with the oxidation of glutathione (Figure 2a )

doi: 10.1369/jhc.2008.951319, 148 TreesukosolY.MoranT